157th largest of 176
Among California’s 176 cities of 50,000+ residents, Santee ranks 157th by population (58,205, July 2025).

Santee has 58,205 residents (−3.1% since 2020), a median household income of $113,394 and 13.7% foreign-born residents.
Photo: Devindad · CC BY-SA 4.0 · Wikimedia CommonsSantee is a city in California. The Census Bureau estimates 58,205 residents in July 2025, compared with 60,037 counted in the 2020 Census. With 17 square miles of land, it had 3,630 people per square mile in 2020. These figures describe the city itself, not its county or metropolitan area.
Pick an indicator to see its long-run evolution.
Census Bureau Population Estimates Program (Vintage 2020 for 2010–2019, Vintage 2025 from 2020).
| Indicator | Value | Year and source |
|---|---|---|
| Population estimate, 2025 | 58,205 | Census Bureau, Vintage 2025 |
| Population estimates base, April 2020 | 60,044 | Census Bureau |
| Population, 2020 Census | 60,037 | Decennial Census |
| Population, 2010 Census | 53,413 | Decennial Census |
| Population, 2000 Census | 52,975 | Decennial Census |
| Land area | 16.5 mi² | Census Gazetteer 2024 |
| Median age | 40.3 years | ACS 2020–2024 |
| Per capita income | $49,612 | ACS 2020–2024 |
| Owner-occupied housing | 72.4% | ACS 2020–2024 |
| Unemployment rate | 4.7% | ACS 2020–2024 |
| Veterans | 4,940 | Civilians 18+ · ACS 2020–2024 |
Comparable indicators for the city, California and the United States.
| Indicator | City | California | U.S. | Reference |
|---|---|---|---|---|
| Median household income | $113,394 | $99,122 | $80,734 | ACS 2020–2024 |
| Median home value | $727,200 | $734,700 | $332,700 | ACS 2020–2024 |
| Median gross rent | $2,250 /month | $2,036 /month | $1,413 /month | ACS 2020–2024 |
| Poverty rate | 7.9% | 12.0% | 12.5% | ACS 2020–2024 |
| Bachelor’s degree or higher | 35.0% | 37.1% | 35.7% | ACS 2020–2024 |
| Foreign-born residents | 13.7% | 27.0% | 14.1% | ACS 2020–2024 |
| Owner-occupied housing | 72.4% | 55.9% | 65.2% | ACS 2020–2024 |
| Median age | 40.3 years | 37.9 years | 38.9 years | ACS 2020–2024 |
Among California’s 176 cities of 50,000+ residents, Santee ranks 157th by population (58,205, July 2025).
The city lost 1,839 residents (−3.1%) from April 2020 to July 2025, 123rd for growth among the state’s 176 large cities.
The census counted 52,975 residents in 2000 and 60,037 in 2020, a +13.3% change.
Median household income is $113,394, +14.4% versus California ($99,122); 59th of 176 large cities.
The median owner-occupied home is worth $727,200, 92nd highest of the state’s 176 large cities.