12th most populous of 15
With 50,508 residents in 2024, Santa Cruz County ranks 12th by population among Arizona's 15 counties and is home to 0.7% of the state's residents.

Santa Cruz County has the largest immigrant share in Arizona (34.2% foreign-born) and the 3rd highest poverty rate (20.2%).
Santa Cruz County is home to 50,508 people (2024 estimate) on 1,236 square miles of land. This page brings together official U.S. Census Bureau population estimates since 2000, the components of change—births, deaths and migration—American Community Survey indicators on income, housing, poverty and education, BEA economic accounts and BLS unemployment.
Pick an indicator to see its long-run evolution.
U.S. Census Bureau: intercensal estimates 2000–2009, Vintage 2020 (2010–2019) and Vintage 2024 (2020–2024), July 1.
| Indicator | Value | Year and source |
|---|---|---|
| Population estimate | 50,508 | 2024 · U.S. Census Bureau |
| Population, 2010 Census | 47,420 | 2010 · U.S. Census Bureau |
| Population, 2000 | 38,589 | July 1, 2000 · Census intercensal |
| Change since 2000 | +30.9% | 2000–2024 · Census |
| International migration | +788 | 2024 · Census Vintage 2024 |
| Domestic migration | −148 | 2024 · Census Vintage 2024 |
| Birth rate | 11.4 per 1,000 | 2024 · calculated |
| Death rate | 7.1 per 1,000 | 2024 · calculated |
| Population rank in Arizona | 12th of 15 | 2024 · calculated |
| Per capita personal income | $50,841 | BEA, 2024 · official |
| Gross domestic product | $2.8 billion | BEA, current dollars, 2024 · official |
| Median household income | $55,217 | ACS 2020–2024 5-year · official |
| Poverty rate | 20.2% | ACS 2020–2024 5-year · official |
| Bachelor’s degree or higher | 23.1% | Age 25+, ACS 2020–2024 5-year · official |
| Foreign-born residents | 34.2% | ACS 2020–2024 5-year · official |
| Median home value | $233,000 | ACS 2020–2024 5-year · official |
| Median gross rent | $829/month | ACS 2020–2024 5-year · official |
| Median age | 37.9 years | ACS 2020–2024 5-year · official |
| Households | 16,966 | ACS 2020–2024 5-year · official |
| Owner-occupied homes | 69.3% | ACS 2020–2024 5-year · official |
Comparable indicators for Santa Cruz County, Arizona and the United States.
| Indicator | County | Arizona | U.S. | Reference |
|---|---|---|---|---|
| Population change 2020–2024 | +6.0% | +5.9% | +2.6% | Census Vintage 2024 |
| Birth rate (per 1,000) | 11.4 | 10.3 | 10.6 | 2024 |
| Death rate (per 1,000) | 7.1 | 9.1 | 9.1 | 2024 |
| Net migration rate (per 1,000) | 12.7 | 13.1 | 8.2 | 2024 |
| Population density (/mi²) | 40.9 | 66.7 | 96.3 | 2024 |
| Per capita personal income | $50,841 | $65,798 | $73,204 | BEA, 2024 |
| Median household income | $55,217 | $79,964 | $80,734 | ACS 2020–2024 5-year |
| Poverty rate | 20.2% | 12.5% | 12.5% | ACS 2020–2024 5-year |
| Bachelor’s degree or higher | 23.1% | 33.3% | 35.7% | Age 25+, ACS 2020–2024 5-year |
| Foreign-born residents | 34.2% | 13.0% | 14.1% | ACS 2020–2024 5-year |
| Median home value | $233,000 | $394,500 | $332,700 | ACS 2020–2024 5-year |
| Median gross rent | $829/month | $1,543/month | $1,413/month | ACS 2020–2024 5-year |
| Median age | 37.9 years | 39.0 years | 38.9 years | ACS 2020–2024 5-year |
| Owner-occupied homes | 69.3% | 67.4% | 65.2% | ACS 2020–2024 5-year |
With 50,508 residents in 2024, Santa Cruz County ranks 12th by population among Arizona's 15 counties and is home to 0.7% of the state's residents.
Its population went from 38,589 in 2000 to 50,508 in 2024, a change of +30.9%, compared with +46.9% for Arizona as a whole.
In the year to July 2024 the county recorded 578 births and 359 deaths, so births outnumbered deaths by 219.
Annual Census estimates since 2000 put the county's highest population in 2024, at 50,508.
Santa Cruz County has about 40.9 residents per square mile of land, ranking 4th of 15 counties; Arizona averages 66.7.
With a median household income of $55,217 (ACS 2020–2024 5-year), the county ranks 12th of 15 Arizona counties; the state median is $79,964.
Its economy produced $2.8 billion of GDP in 2024 (BEA), 11th largest among 15 Arizona counties.
Real GDP grew 1.5% in 2024, adjusted for inflation (BEA, chained 2017 dollars).